Construction of giant 2D and 3D supramolecular architectures – Dr Xiaopeng Li

11am, Wednesday 28 October

Online event

Construction of giant 2D and 3D supramolecular architectures – Dr Xiaopeng Li

We're looking forward to welcoming Dr Xiaopeng Li from Shenzhen University for another inspirational guest lecture!

“Due to its highly directional and predictable feature, coordination-driven self-assembly has evolved into a well-established methodology for constructing 2D and 3D supramolecules. Up to date, this field has matured in the context of a large variety of macrocycles and polyhedra, which however, still suffered from a lack of complexity and thus were unable to reach the high degrees of functionality found in natural systems. With the goal of assembling structures with high complexity, we pushed the limits of coordination self-assembly through constructing a series of giant 2D and 3D supramolecular architectures. First, multi-armed building blocks were synthesised using pyrylium and pyridinium salts chemistry for the self-assembly of 2D nested concentric hexagons, or Kandinsky circles, which showed high antimicrobial activity. Second, step-wise strategy was utilised to combine folding and self-assembly together to construct fuzzy supramolecular hexagonal grids (diameter > 20 nm, MW > 65 kDa) with intrinsically ordered and disordered domains. Third, pre-assembled supramolecular polyhedra with precisely-controlled shapes and sizes could further assemble into double-helical nanowires with a non-natural parastichy pattern. In conclusion, through further understanding of self-assembly of supramolecules, our research could advance the design, synthesis and self-assembly of new synthetic materials with molecular level precision.”

​Dr. Xiaopeng Li received his B.S. degree in Chemistry at Zhengzhou University, China in 2004, earned his Ph.D. in Chemistry in 2008 at Cleveland State University, and then worked as a postdoc fellow at University of Akron. He started his independent career at Texas State University in 2012, then moved to University of South Florida as Assistant Professor in 2016, then was promoted to Associate Professor with tenure in 2018. In 2020, he returned to China and joined Shenzhen University as Tencent Founders Alumni Professor. Shenzhen University is located in Shenzhen, one of the most dynamic cities in China. His specific research interests include 1) self-assembly of giant metallo-supramolecules to bridge mathematic geometry and supramolecular chemistry; 2) seeking novel application of metallo-supramolecules; 3) advancing supramolecular chemistry characterisation using mass spectrometry. Dr. Li has authored or coauthored over 180 research publications, of which 90 are published in the top-tier journals, including Science, Nature, Nature Chem., J. Am. Chem. Soc., Angew. Chem., Nature Commun., and Proc. Natl. Acad. Sci. U.S.A. He received Cram Lehn Pedersen Prize 2019 in Supramolecular Chemistry.

Non-drinking event.

This event is accessible to all.